Forxiga Tablets 5 contain Dapagliflozin, a medication primarily used to treat Type 2 Diabetes, and also for chronic kidney disease (CKD) and heart failure in adults. It belongs to a class of drugs called SGLT2 inhibitors (sodium-glucose cotransporter-2 inhibitors).
Key Information about Forxiga Tablets 5:
- Active Ingredient: Dapagliflozin
- Class: SGLT2 Inhibitor
- Indications:
- Type 2 Diabetes: Helps lower blood sugar by preventing the kidneys from reabsorbing glucose back into the bloodstream. Instead, excess glucose is excreted in the urine.
- Chronic Kidney Disease (CKD): Helps reduce the progression of kidney damage in patients with kidney disease.
- Heart Failure: Reduces the risk of hospitalization due to heart failure and improves heart function.
- Mechanism of Action:
- Dapagliflozin works by inhibiting SGLT2, a protein in the kidneys responsible for reabsorbing glucose back into the bloodstream. This leads to increased glucose excretion in the urine, helping to control blood sugar levels.
- It also has benefits on the heart and kidneys, helping to reduce the risk of kidney disease progression and hospitalizations due to heart failure.
Dosage:
- The usual dose of Forxiga Tablets 5 is 5mg once a day.
- In some cases, the dose may be increased to 10mg once a day, based on the patient’s condition and doctor’s recommendations.
- It can be taken with or without food.
Side Effects:
Common side effects of Forxiga include:
- Urinary tract infections (UTIs)
- Increased urination
- Thirst and dehydration
- Low blood pressure
- Dizziness
- Increased levels of potassium in the blood (hyperkalemia)
Serious side effects (rare but possible):
- Ketoacidosis (high ketone levels in the blood)
- Kidney issues or acute kidney injury
- Fournier’s gangrene, a rare but serious infection in the genital area
- Bone fractures (due to dehydration-related effects)
Precautions:
- Kidney function: Not recommended for patients with severe kidney impairment.
- Pregnancy and Breastfeeding: Should not be used during pregnancy, and caution should be exercised while breastfeeding.
- Risk of Dehydration: Ensure adequate hydration, especially in elderly patients or those with low blood pressure.
Storage:
- Store Forxiga tablets in a cool, dry place at room temperature. Keep them away from moisture and out of reach of children.
Conclusion:
Forxiga (Dapagliflozin) is a highly effective medication for managing Type 2 diabetes, chronic kidney disease, and heart failure, with added benefits in improving cardiovascular health and slowing kidney disease progression. Always follow your healthcare provider’s guidance on dosage and usage.
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