Bavencio Injection is a prescription medication used in cancer immunotherapy. It contains the active ingredient Avelumab, a programmed death-ligand 1 (PD-L1) blocking antibody. Bavencio works by enhancing the immune system’s ability to recognize and destroy cancer cells.
Key Uses:
Bavencio Injection Avelumab is approved for the treatment of:
- Metastatic Merkel Cell Carcinoma (MCC): A rare and aggressive type of skin cancer.
- Advanced or Metastatic Urothelial Carcinoma (UC): Cancer of the bladder and urinary tract in patients who have previously received platinum-based chemotherapy.
- Advanced Renal Cell Carcinoma (RCC): Administered in combination with axitinib for patients with advanced kidney cancer.
Mechanism of Action:
Bavencio Injection Avelumab blocks PD-L1, a protein expressed by some cancer cells to evade immune detection. By inhibiting this pathway, it helps immune cells (T-cells) identify and attack tumors.
Administration:
- Route: Intravenous (IV) infusion.
- Schedule: Typically infused over 60 minutes every 2 weeks.
- Administered under strict medical supervision in a hospital or clinic.
Common Side Effects:
- Fatigue
- Nausea
- Infusion-related reactions (fever, chills, shortness of breath)
- Immune-related conditions (e.g., inflammation of the lungs, liver, or thyroid)
Important Considerations:
- Patients should inform their doctor about any autoimmune diseases, organ transplants, or pre-existing conditions.
- Regular monitoring of immune function, liver function, and overall health is necessary during treatment.
- It is essential to report any unusual symptoms promptly.
Storage:
- Store between 2°C and 8°C (36°F to 46°F).
- Do not freeze or shake. Protect from light.
Conclusion:
Bavencio Injection Avelumab represents a significant advancement in cancer treatment, offering hope to patients with certain advanced cancers. Consult your healthcare provider to discuss whether Bavencio is a suitable option for your condition.
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