Actemra 400 mg Injection is a prescription medication primarily used to treat autoimmune conditions such as rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), and giant cell arteritis (GCA). It contains tocilizumab, a monoclonal antibody that blocks the action of interleukin-6 (IL-6), a protein that contributes to inflammation in the body. This helps reduce symptoms such as pain, swelling, and stiffness in joints while slowing disease progression.
Key Uses:
- Rheumatoid Arthritis (RA): Helps reduce inflammation and joint damage in adults with moderate to severe RA.
- Juvenile Idiopathic Arthritis (JIA): Used in children aged 2 years or older to manage systemic or polyarticular forms of arthritis.
- Giant Cell Arteritis (GCA): Treats inflammation of the large arteries in adults.
- Cytokine Release Syndrome (CRS): Manages severe CRS caused by CAR-T cell therapy in cancer treatment.
How It Works:
Actemra contains tocilizumab, which inhibits the activity of IL-6. By blocking IL-6, it helps control inflammation and prevents the immune system from attacking healthy tissues.
Dosage:
- Administered as an intravenous (IV) infusion by a healthcare professional.
- Dosage depends on the patient’s weight, condition, and doctor’s recommendation.
- Typically given every 2 to 4 weeks.
Common Side Effects:
- Injection site reactions
- Upper respiratory tract infections
- Headache or dizziness
- Increased liver enzymes
- Risk of infections (e.g., tuberculosis)
Precautions:
- Regular monitoring of liver function and blood counts is required.
- Patients should inform their doctor about any history of infections, liver disease, or allergies.
- Avoid using Actemra during active infections or if you have a weakened immune system.
Actemra 400 mg Injection is an effective treatment for autoimmune diseases, improving quality of life for those with chronic inflammation. Always consult a healthcare provider for proper guidance and monitoring during treatment.
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