tenofovir disoproxil fumarate tablets 300 mg

$250

Tenofovir Disoproxil Fumarate Tablets 300 mg are an antiviral medication used to treat and manage chronic hepatitis B infection and HIV-1 infection. It is a prodrug of tenofovir, a nucleotide reverse transcriptase inhibitor (NRTI), which works by inhibiting the reverse transcriptase enzyme essential for viral replication.

Key Information about Tenofovir Disoproxil Fumarate 300 mg Tablets:

  • Brand Names: Viread, among others.
  • Indications:
    • Chronic Hepatitis B: Used in adults and children over 12 years old to reduce the amount of the hepatitis B virus (HBV) in the blood and prevent liver damage.
    • HIV-1 Infection: Used as part of a combination antiretroviral therapy (ART) regimen for adults and children over 2 years old to manage HIV infection.
  • Dosage:
    • Hepatitis B: The typical dose for adults is 300 mg once daily.
    • HIV-1 Infection: Typically, 300 mg once daily, often as part of a combination regimen with other antiretroviral drugs.

Mechanism of Action:

  • Tenofovir disoproxil fumarate is converted in the body to tenofovir, which inhibits the reverse transcriptase enzyme. By blocking viral replication, it lowers the viral load and helps prevent damage to the liver in hepatitis B or reduces the viral load in HIV.

Side Effects:

Common side effects can include:

  • Nausea
  • Diarrhea
  • Headache
  • Fatigue

Serious side effects may include:

  • Kidney problems (e.g., renal impairment)
  • Lactic acidosis (rare but severe)
  • Bone loss or fractures
  • Liver toxicity

Precautions:

  • Kidney function: Tenofovir may cause kidney problems, so kidney function should be monitored regularly, especially in patients with pre-existing kidney issues.
  • Bone health: Prolonged use can affect bone mineral density.
  • HIV Resistance: If taken alone, it can lead to the development of drug-resistant HIV, so it is always prescribed as part of a combination therapy for HIV.
  • Pregnancy: Tenofovir should only be used during pregnancy if the benefits outweigh the risks.

Storage:

  • Store tablets at room temperature, away from moisture and heat.

Before starting Tenofovir Disoproxil Fumarate, consult with a healthcare provider to ensure proper monitoring and minimize the risk of side effects.

 

Website: Jyotilifecar